Type: Immune Globulin Intravenous; liquid solution for intravenous use
Therapies & Conditions: Used to strengthen the immune system in order to lower the risk of infection; indicated for the treatment of chronic immune thrombocytopenic purpura (ITP), humoral immunodeficiencies (PI) such as congenital agammaglobulinemia, common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome and severe combined immunodeficiencies.
Administration: Typically administered at a total dose of 2 g/kg, divided into two doses of 1 g/kg (10mL/kg) given on two consecutive days.
Method: Intravenous (IV) infusion
Side Effects: The most common adverse reactions include headache, fever and increased heart rate. The use of Octagam can result in kidney problems and blood clots, and issues are more likely for those with risk factors such as heart disease or blood circulation problems.
For more detailed information on Octogam, please visit FDA.gov
Frequently Asked Questions
- Is home infusion therapy safe?
Home and alternate site infusion therapy is a proven, safe and effective alternative to hospital inpatient care.[*]Bhole, M. V., Burton, J., & Chapel, H. M. (2008). Self-infusion programmes for immunoglobulin replacement at home: Feasibility, safety and efficacy. Immunology and Allergy Clinics of North America,28(4), 821-832. [*]Souayah, N., Hasan, A., Khan, H., et al. (2011). The safety profile of home infusion of intravenous immunoglobulin in patients with neuroimmunologic disorders.Journal of Clinical Neuromuscular Disease, 12(suppl 4), S1-10. For most people, receiving treatment at home or in an alternate treatment setting, like an infusion suite, is preferable to hospital inpatient care. It can provide comfort and convenience for patients and offers less interruption to their daily activities. It can also be a cost-effective alternative to expensive hospital stays.[*]Home infusion therapy: Differences between Medicare and private insurers’ coverage. (2010, June). United States Government Accountability Office Report to Congressional Requesters. Accessed July 23, 2012: http://www.gao.gov/assets/310/305261.pdf. [*]Einodshofer, M. (2012). A plan for medical specialty medications – increase member access, affordability and outcomes while decreasing plan costs. Presented at: 2012 Pharmacy Benefit Management Institute Annual Drug Benefit Conference; 2012 Feb. 22-24; Scottsdale, Ariz.
- What is infusion therapy?
Infusion therapy involves the administration of medication through a needle or catheter. It is usually prescribed when a patient’s condition cannot be treated with oral medication. Read more about infusion therapy treatments.
- What types of therapy can be delivered intravenously in the home?
Option Care Health specializes in providing a wide range of home infusion therapies, including but not limited to:
AI – Anti-infective infusion therapy (antibiotic, antifungal, antiviral therapy)
NS – Nutrition support infusion therapy (enteral and parenteral nutrition)
IG – Immunoglobulin infusion therapy (immunodeficiency and autoimmune therapy)
HF – Heart failure infusion therapy (inotropic therapy)
BD – Bleeding disorders infusion therapy (factor replacement therapy)